Influence of tea pigment on cardiac activity in exsomatized toads of myocardial ischemia
10.3969/j.issn.1671-8348.2018.05.004
- VernacularTitle:茶色素对心肌缺血离体蟾蜍心脏活动的影响
- Author:
Yu ZHANG
1
;
Shufang DAI
;
Zhidan WANG
;
Yiping SUN
;
Lei FU
;
Kemin LIU
;
Liang ZHU
;
Shulong ZHANG
Author Information
1. 大连医科大学基础医学院
- Keywords:
tea pigment;
myocardial ischemia;
myocardial contractility;
electrocardiography;
heart rate
- From:
Chongqing Medicine
2018;47(5):588-589,593
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of tea pigment on myocardial contractility,electrocardiogram(ECG) and heart rate in exsomatized toads under the condition of myocardialischemia.Methods Sixty toads were divided into the normal exsomatized toad heart group(A) and myocardial ischemia toad heart(B).Then the group A was re-divided into the Ringer's solution group (A1),tea pigment low dose(200 mg/L) group(A2) and the high dose(400 mg/L) group(A3);the group B was re-divided into the pituitrin model group(B1),pituitrin + tea pigment low dose(200 mg/L) group(B2) and high dose(400 mg/L) group(B3).The BL-420S biological function experiment system was used to record the myocardial contractile force and ECG change curve of exsomatized toad.Results Compared with the group A1,the myocardial contractility in the group A3 was obviously increased(P＜0.05),the difference in the group A2 had no statistical significance(P＞0.05);the QRS peak value of ECG and heart rate had no statistically significant difference(P＞0.05);compared with the group A1,the myocardial contractility,ECG QRS peak value and heart rate in the group B1 were significantly decreased(P＜0.05);compared with the group B1,the myocardial contractility,ECG QRS peak value and heart rate in the group B2 and B3 were significantly increased(P＜0.05).Conclusion Tea pigment can obviously improve the decrease of the exsomatized toad cardiac activity caused by myocardial ischemia.
