Relationship between obesity and serum testosterone level in 1 166 adult males
10.3969/j.issn.1671-8348.2018.05.002
- VernacularTitle:1166例成年男性肥胖与血清睾酮水平的关系
- Author:
Shimin XIONG
1
;
Fangwei LIU
;
Yongjun SHI
;
Na YU
;
Xubo SHEN
;
Honggang LI
;
Chengliang XIONG
;
Yuanzhong ZHOU
Author Information
1. 遵义医学院公共卫生学院卫生毒理学教研室
- Keywords:
obesity;
serum testosterone;
adult;
male
- From:
Chongqing Medicine
2018;47(5):580-583
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between obesity and serum testosterone level among community adult males.Methods The stratified cluster sampling method was adopted to extract 1 166 male residents aged 20 years old and over in Zunyi City and conduct the questionnaire survey and physical examination.Fasting venous blood samples were collected for detecting the serum total testosterone(TT),sex hormone binding globulin(SHBG) and luteinizing hormone(LH).Then free testosterone index(cFT),free testosterone index(FTI) and testosterone secreting index(TSI) were calculated.Results The average levels of serum TT,SHBG,cFT,FTI,TSI and LH in 1 166 adult males were(16.83±4.90)nmol/L,(42.15 ± 20.21)nmol/L,(0.31 ±0.10)nmol/L,(0.46 ± 0.19) IU/L,(3.40 ± 2.04) IU/L and(6.77 ± 5.14) IU/L respectively;the Pearson correlation analysis showed that WHtR,BMI and WC were negatively correlated with TT,SHBG,TSI and LH,and were positively correlated with FTI,WHtR was negatively correlated with cFT,BMI and WC were negatively correlated with LH,the differences were statistically significant(P＜0.05).The multivariate linear regression analysis shown that WHtR was negatively correlated with TT,SHBG,TSI and LH;and was positively correlated with FTI,the differences were statistically significant(P＜0.01).Conclusion Adult male central obesity may be associated with the decrease of serum TT,SHBG,TSI and LH levels,and increase of FTI level.
