Safety and effectiveness of combination application of thrombus aspiration and intracoronary injection of tirofiban
10.3969/j.issn.1671-8348.2018.02.022
- VernacularTitle:联合应用血栓抽吸及冠状动脉内注射替罗非班的安全性和有效性
- Author:
Tao GENG
1
;
Zhiyuan SONG
;
Bingxun WANG
;
Zesheng XU
Author Information
1. 天津医科大学沧州市中心医院心内科
- Keywords:
myocardial infarction;
platelet glycoprotein GP Ⅱb-Ⅲa complex;
angioplasty,transluminal,percutaneous coronary;
thrombus aspiration;
tirofiban
- From:
Chongqing Medicine
2018;47(2):211-213,216
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the interventional therapy effect of combination application of thrombus aspiration and intracoronary injection of tirofiban for treating heavy thrombosis burden of infarction related vessel in the patients with acute anterior myocardial infarction.Methods The patients with acute anterior myocardial infarction undergone direct primary percutaneous coronary intervention in the hospital were retrospectively analyzed.The group A received simple thrombus aspiration during transcutaneous PCI and the group B received the combination treatment of thrombus aspiration and intracoronary injection of tirofiban in direct PCI.Results The patients with myocardial perfusion grade less than 3 during thrombolysis during myocardial infarction(TIMI) in the group B were significantly less than those in the group A(P＜0.05).The cardiac magnetic resonance imaging(MRI) results indicated that the area of myocardial infarction in the group B was smaller than that in the group A(P＜0.05).The color echocardiography results showed that the left ventricular diastolic volume(LVDV) and left ventricular ejection fraction(LVEF) in the group B were significantly better than those in the group A(P＜0.05).Conclnsion The combination application of thrombus aspiration and intracoronary injection of tirofiban is safe and effective in direct PCI.
