Influence of depression on glycemic control in patients with type 2 diabetes mellitus

VernacularTitle:2型糖尿病患者抑郁情绪对血糖控制的影响
Author: Yanfeng ZHEN ¹ ; Xiaogang ZHAI ; Hui FANG ; Xingyu LIU ; Gang XU ; Jinli TIAN ; Yazhong ZHANG ; Jing XU ; He ZHANG ; Lei ZHOU
Author Information

1. 河北省唐山市工人医院内分泌科 063000
Keywords: diabetes mellitus,type 2; depression; HbA1c; self-rating depression scale
From: Chongqing Medicine 2018;47(1):35-36
CountryChina
Language:Chinese
Abstract: Objective To investigate the influence of depression on glycemic control in the patients with type 2 diabetes mellitus(T2DM).Methods The Zung self-rating depression scale(SDS) was used to assess depression.A total of 276 cases of T2DM were divided into the group A(SDS standard score ≥53 points) and B(SDS standard score ＜53points).The levels of HbA1c,FPG,HOMA-IR,etc.were compared between the two groups,and the influencing factors of glycemic control in T2DM patients were analyzed.Results In the patients with T2DM,the SDS standard score was correlated with HbA1c(r=0.26,P＜0.05).The multivariate regression analysis showed that the SDS standard score was still correlated with HbA1c (β =0.30,t =5.1,P＜ 0.05).The HbA1c level in the group A was higher than that in the group B(t=3.685,P＜0.05);after correcting the factors of sex,age and education,the HbA1c level in the group A was still higher than that in the group B(F=47.8,P＜0.05).Conclusion The depression mood is adverse to glycemic control in T2DM patients.