Primary systemic amyloidosis with chronic diarrhea onset: report of one case and review of literature

VernacularTitle:以慢性腹泻起病的原发性系统性淀粉样变性一例并文献复习
Author: Ran ZHANG ¹ ; Quanshun WANG ; Yu ZHAO ; Haiyan ZHU
Author Information

1. 解放军总医院血液科
Keywords: Amyloidosis; Diarrhea; Immunoglobulin light chains; Bortezomib; Hematopoietic stem cell transplantation
From: Journal of Leukemia & Lymphoma 2018;27(11):660-663,669
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical features, diagnosis and treatment of chronic diarrhea with primary systemic amyloidosis (AL). Methods The clinical experience of an AL patient with chronic diarrhea who was admitted to chinese PLA General Hospital in November 2017 was presented, and the related literature was reviewed. Results The patient was definitely diagnosed as AL with chronic diarrhea onset;after treatment with VCD regimen, the condition was improved obviously and achieved complete remission. Conclusion AL patient with chronic diarrhea onset needs to undergo various detections to make a clear diagnosis and differential diagnosis, and the bortezomib-based treatment scheme can achieve good curative effect.