Progress of autophagy in treatment of chronic myelogenous leukemia
10.3760/cma.j.issn.1009-9921.2018.07.018
- VernacularTitle:自噬在慢性粒细胞白血病治疗中的研究进展
- Author:
Jun BAI
1
;
Bo HE
;
Mouzhen HUANG
;
Liansheng ZHANG
Author Information
1. 730030,兰州大学第二医院血液科甘肃省血液病重点实验室
- Keywords:
Leukemia,myelogenous,chronic;
Autophagy
- From:
Journal of Leukemia & Lymphoma
2018;27(7):441-444
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy plays an important role in the occurrence,progression and treatment of cancer,neurodegenerative,autoimmune and inflammatory diseases.Recent years,autophagy has become a new hot spot in tumor area.Chronic myelogenous leukemia (CML) is a common hematopoietic malignancy;while autophagy is involved in its development,as well as targeting drug tyrosine kinase inhibitor resistance mechanisms,regulating autophagy provide a new direction for the treatment of CML.The intensive study of the relation between cell autophagy and cancer will help to overcome cancer.This article offers an up-to-date comprehensive review of autophagy and CML.
