Distribution, drug resistance and drug sensitivity of pathogens in patients with intra-abdominal infection
10.19405/j.cnki.issn1000-1492.2018.03.027
- VernacularTitle:腹腔感染患者病原菌分布及耐药性和药敏分析
- Author:
Jianfei PAN
1
;
Hong ZHANG
;
Chengcai DAI
Author Information
1. 安徽医科大学第一附属医院急诊医学科
- Keywords:
intra-abdominal infection;
pathogen distribution;
drug resistance;
drug sensitivity
- From:
Acta Universitatis Medicinalis Anhui
2018;53(3):453-457
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution of pathogens and the results of drug sensitivity test in patients with intra-abdominal infection, and to provide theoretical basis for the rational selection of anti-infective programs. Methods The pathogenic bacteria culture and drug sensitivity test results of peritoneal fluid or drainage fluid in hospitalized patients with intra-abdominal infection were retrospectively analyzed. Results 405 cases of positive culture results were obtained in 3 509 cases of intra-abdominal infection specimens. A total of 436 strains of pathogens, including 268 strains of Gram-negative bacteria (61.47％), 151 strains of Gram-positive bacteria(34. 63％), 17 strains of Fungi (3. 90％). The top five were Escherichia coli (22. 25％), Acinetobacter baumannii (10. 09％), Klebsiella pneumoniae (9. 86％), Enterococcus faecium (7. 80％), Staphylococcus aureus(4. 13％). The extended spectrum β-lactamas rates of Escherichia coli and Klebsiella pneumoniae were 58. 76％ and 16. 28％, respectively. The multi-drug resistant strains of Acinetobacter baumannii were 79. 55％. Vancomycin resistant strains were detected in Enterococcus faecium (8. 82％), the detection rate of methicillin-resistant Staphylococcus aureus (MRSA) in Staphylococcus aureus was 72. 22％, and the detection rate of methicillin-resistant Staphylococcus aureus (MRCNS) in coagulase-negative Staphylococci was 51. 92％. Conclusion The main pathogens of intra-abdominal infection is Escherichia coli, followed by Acinetobacter baumannii, Klebsiella pneumoniae, Enterococcus faecium and Staphylococcus aureus, the detection rate of MRSA and MRCNS is high. The overall drug resistance of intra-abdominal infection is serious.
