Radio-Guided Parathyroidectomy for Primary Hyperparathyroidism: Three cases.
- Author:
Jung Hyun YANG
1
;
Hai Lin PARK
;
Sang Dal LEE
;
Seok Jin NAM
;
Byung Tae KIM
Author Information
1. Department of General Surgery, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Primary hyperparathyroidism;
Radio-guided parathyroidectomy
- MeSH:
Anesthesia, Local;
Humans;
Hyperparathyroidism, Primary*;
Incidence;
Korea;
Parathyroid Neoplasms;
Parathyroidectomy*;
Rare Diseases;
Thyroid Gland
- From:Journal of the Korean Surgical Society
2000;59(4):539-544
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although primary hyperparathyroidism is a rare disease in Korea, the incidence is increasing gradually due to increased concern and the development of laboratory and imaging techniques. Previous radiological imaging studies for localization of a parathyroid adenoma have been generally unreliable. Recently, preoperative administration of Tc-99m sestamibi has improved detection of parathyroid adenomas. Combining preoperative administration of the sestamibi radionuclide with an intraoperative gamma probe can identify the exact location of a parathyroid adenoma successfully and facilitate a safe and efficient operation under local anesthesia. Limited exploration provides a better cosmetic result while decreasing the potential complications of bilateral exploration. Also, an obvious indication for radio-guided para thyroid surgery with a minimal approach may well be the high-risk patient who cannot tolerate a general anesthestic or an extensive surgical approach. We report three cases of primary hyperparathyroidism which were successfully treated with intraoperative radio-guided parathyroid surgery. These parathyroid surgery can be enhanced especially in the future, when and if an efficient and cost-effective intraoperative PTH assay becomes available.