Surface-enhanced Raman nanoparticles for tumor theranostics applications.
10.1016/j.apsb.2018.03.007
- Author:
Yangyang LI
1
;
Qiaolin WEI
1
;
Fei MA
1
;
Xin LI
2
;
Fengyong LIU
2
;
Min ZHOU
1
Author Information
1. Department of Nuclear Medicine & Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
2. Department of Interventional Radiology, Chinese PLA General Hospital, Beijing 100853, China.
- Publication Type:Journal Article
- Keywords:
Cancer imaging;
Nanoparticles;
Raman spectroscopy;
SERS;
Theranostics
- From:
Acta Pharmaceutica Sinica B
2018;8(3):349-359
- CountryChina
- Language:English
-
Abstract:
Raman spectroscopy, amplified by surface-enhanced Raman scattering (SERS) nanoparticles, can provide an imaging modality due to its high molecular specificity, high sensitivity, and negligible autofluorescence. The basis, composition, and methodologies developed for SERS nanoparticles are herein described. The research hotspots that are the focus in this paper are tumor imaging-guided theranostics and biosensing. The next breakthrough may be the development of biocompatible SERS nanoparticles and spectroscopic devices for clinical applications.