A Case of Life-Threatening Supraventricular Tachycardia Related to Flecainide Toxicity.
- Author:
Sang Soo CHEON
1
;
Joon Hyuk SONG
;
Myung Hwan BAE
;
Jang Hoon LEE
;
Dong Heon YANG
;
Hun Sik PARK
;
Shung Chull CHAE
Author Information
1. Division of Cardiology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. ddhyang@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Flecainide;
Hemoperfusion;
Extracorporeal membrane oxygenation
- MeSH:
Extracorporeal Membrane Oxygenation;
Flecainide*;
Hemodynamics;
Hemoperfusion;
Humans;
Renal Insufficiency;
Shock;
Sodium;
Tachycardia, Supraventricular*
- From:Korean Journal of Medicine
2014;87(1):72-76
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Flecainide acetate is a potent class Ic anti-arrhythmic drug with a major sodium channel-blocking effect. Flecainide toxicity can cause myocardial impairment and precipitate circulatory collapse, particularly in patients with renal failure. Electrical and hemodynamic deterioration during flecainide toxicity may not respond to conventional treatments. We report the successful management of flecainide toxicity using extracorporeal membrane oxygenation (ECMO), hemoperfusion, and bicarbonate administration maintaining alkalinity.