Chemical constituents from traditional Uighur herbal medicine Elaeagnus angustifolia flowers.
10.19540/j.cnki.cjcmm.20180115.020
- Author:
Xiao-Yu CHEN
1
;
Jian-Xin HAN
1
;
Yu-Shuang LIU
1
;
Aisa HAJIAKBER
1
;
Tao YUAN
1
Author Information
1. The Key Laboratory of Plant Resources and Chemistry of Arid Zone, Chinese Academy of Sciences, State Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, China.
- Publication Type:Journal Article
- Keywords:
COX;
Elaeagnus angustifolia;
anti-inflammation;
aromatic glycoside;
traditional Uighur medicine
- From:
China Journal of Chinese Materia Medica
2018;43(9):1749-1753
- CountryChina
- Language:Chinese
-
Abstract:
Seven aromatic glycosides (1-7), including four phenylethanol glycosides, one phenylmethanol glycoside, one phenylpropane glycoside and one benzoside, were isolated from the methanolic extract of Uighur Medicine Elaeagnus angustifolia flowers. Their structures were elucidated based on the analysis of spectroscopic data (1D, 2D NMR and HR-MS). Compound 1 is a new compound, named as angustifol A. Six known compounds were identified as 2-phenylethyl-O-β-D-glucopyranoside(2), salidroside (3), vanillic acid 4-O-β-D-glucopyranoside(4), vanilloloside (5), (Z)-isoconiferin (6), 2-phenylethyl-6-O-α-L-arabinofuranosyl-β-D-glucopyranoside (7). Compounds 2-7 were isolated from the genus Elaeagnus for the first time. In vitro anti-inflammatory assays revealed that none of these compounds showed good COX inhibitory activities.