Replication and Pathology of Duck Influenza Virus Subtype H9N2 in Chukar.

Author: Yin Chuan ZHU ¹ ; Bin ZHANG ¹ ; Zeng Hui SUN ¹ ; Xi Jing WANG ¹ ; Xiao Hui FAN ¹ ; Ling Xi GAO ¹ ; Ying LIANG ¹ ; Xiao Yan CHEN ¹ ; Zeng Feng ZHANG ¹
Author Information

1. Department of Microbiology, Guangxi Medical University, Nanning 530021, Guangxi, China.
Publication Type:Journal Article
MeSH: Animals; Galliformes; Influenza A Virus, H9N2 Subtype; pathogenicity; physiology; Influenza in Birds; virology; Respiratory System; pathology; virology; Virus Replication; physiology
From: Biomedical and Environmental Sciences 2018;31(4):306-310
CountryChina
Language:English
Abstract: To investigate the susceptibility of Chukars to duck avian influenza virus H9N2 and explore their role in interspecies transmission of influenza viruses. Chukars were inoculated with duck avian influenza viruses H9N2. The present study demonstrated that inflammatory lesions and virus antigen were present in the trachea, bronchus, and parabronchus, and the viruses could be isolated from throat swabs and lung tissue homogenate supernatants. At 14 d post virus inoculation, anti-H9 influenza virus antibody in the serum was detected. The results indicated that Chukars are susceptible to duck avian influenza virus and serve as an intermediate host, thereby facilitating viral gene evolution and supporting the need for continued surveillance of epidemiology and evolution of the influenza virus in Chukars.