Association between Physical Activity and Telomere Length in a North Chinese Population: A China Suboptimal Health Cohort Study.

Li Xiang Ding; Yan Hong Zhang; Xi Zhu XU; Jie Zhang; Ming Sung; Di Liu; Zhong Yao Zhao; Yong Zhou; Qun Zhang; You Xin Wang

Return

Association between Physical Activity and Telomere Length in a North Chinese Population: A China Suboptimal Health Cohort Study.

Author: Li Xiang DING ¹ ; Yan Hong ZHANG ² ; Xi Zhu XU ³ ; Jie ZHANG ⁴ ; Ming SUNG ⁴ ; Di LIU ⁴ ; Zhong Yao ZHAO ⁴ ; Yong ZHOU ⁵ ; Qun ZHANG ⁶ ; You Xin WANG ⁴
Author Information

1. Department of Orthopedics Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
2. Department of Internal Medicine, Weifang Material and Child Health Hospital, Weifang 261011, Shandong, China.
3. School of Public Health, Taishan Medical University, Taian 271016, Shandong, China.
4. Beijing Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing 100069, China.
5. Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
6. Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Publication Type:Journal Article
Keywords: Chinese; Physical activity; Relative telomere length; Telomere length
MeSH: Adult; Asian Continental Ancestry Group; genetics; China; Cohort Studies; Cross-Sectional Studies; Exercise; physiology; Female; Humans; Male; Middle Aged; Telomere; Young Adult
From: Biomedical and Environmental Sciences 2018;31(5):394-398
CountryChina
Language:English
Abstract: Several studies have demonstrated an association between physical activity and telomere length; however, the association remains inconsistent. A cross-sectional study consisting of 588 participants (375 females, median age of 33.8 years) was carried out to investigate the association between telomere length and physical activity in a general population from North China. The results show that relative telomere length is not significantly different in participants in the northern Chinese population with different levels of physical activity, either in the model only adjusted for age (F = 2.127, P = 0.120) or in the model adjusted for demographics and lifestyle (F = 1.227, P = 0.294). The gender-stratified analysis also produced insignificant results. Our study confirmed a non-significant association between physical activity and telomere length in the northern Chinese population, which adds to the inconsistent association between physical activity and telomere length across different ethnic populations.