Effects of Infrasound on Gastric Motility, Gastric Morphology and Expression of Nitric Oxide Synthase in Rat.

Author: Ju Hui ZHAO ¹ ; Jin Hai WANG ¹ ; Jin Yan LUO ¹ ; Xiao Yan GUO ¹ ; Yan WANG ¹ ; Yan CHENG ¹
Author Information

1. Department of Gastroenterology, Second Affiliated Hospital of Xi'an Jiao Tong University, Xi'an 710004, Shaanxi, China.
Publication Type:Journal Article
MeSH: Animals; Gastrointestinal Motility; Gene Expression Regulation, Enzymologic; Male; Nitric Oxide Synthase; metabolism; Rats; Sound; adverse effects; Stomach
From: Biomedical and Environmental Sciences 2018;31(5):399-402
CountryChina
Language:English
Abstract: Infrasound widely exists in nature, our living condition, productive and traffic environment. Gastrointestinal tract is relatively sensitive to infrasound. However, the effect of infrasound on gastrointestinal function is unclear. Therefore, the purpose of our study was to observe the effects of infrasound on gastric motility and gastric morphology and to assess the expression of nitric oxide synthase (NOS) in gastric antrum after exposure to infrasound of 8 Hz - 130 dB for 2 hours per day for 14 consecutive days. Gastric motility was assessed by gastric fluid-emptying rate. Gastric morphology was evaluated by HE. The expression of NOS was measured by tissue microarray technology. The results would contribute to understand the role of infrasound in gastroenterology, and help to explain the mechanism of infrasound on gastroenterology.