Amaryllidaceae alkaloids from Lycoris radiata.
- Author:
Jiang HU
1
;
Yan LIU
1
;
Qiang LI
1
;
Li-Fang ZHANG
1
;
Nian-Hua JING
1
;
Jun-You SHI
1
;
Tao LYU
1
;
Si YIN
1
;
Tian-Feng PENG
1
;
Shan-Hu HAO
1
Author Information
- Publication Type:Journal Article
- Keywords: Amaryllidaceae; Lycoris radiata; alkaloid; chemical constitutent
- From: China Journal of Chinese Materia Medica 2018;43(10):2086-2090
- CountryChina
- Language:Chinese
- Abstract: Three aporphine-type alkaloids (1-3), three lycorine-type alkaloids (4-6), two crinane type alkaloids (7, 8) and one phenanthridine-type alkaloid (9) were isolated from the chloroform soluble fraction of 70% ethanol extract of the bulbs of Lycoris radiata through various column chromatographies over silica gel, ODS, Sephadex LH-20 and MCI. Their structures were elucidated as (+)-N-methoxylcarbonyl-1,2-methylenedioxyl-isocorydione (1), isocorydione (2), 8-demethyl-dehydrocrebanine (3), (+)-3-hydroxy-anhydrolycorine N-oxide (4), vasconine (5), pancratinine D (6), yemenine A (7), 11-O-acetylhaemanthamine (8), and 5,6-dihydro-5-methyl-2-hydroxyphenanthridine (9) based on their chemical and physicochemical properlies and spectroscopic data. Compound 1 was a new compound and alkaloids 2-9 were isolated and identified from this plant for the first time.
