Purtscher-like retinopathy associated with antibiotic anaphylaxis.
- Author:
Zhi-Xuan HUANG
1
;
Zhi-Bing ZENG
;
Zhu-Ping XU
Author Information
1. Departmen of Ophthalmology, West China Hospital of Sichuan University, Chengdu 610041, China. E-mail: kai8xuan@163.com.
- Publication Type:Journal Article
- From:
Journal of Southern Medical University
2018;38(3):239-242
- CountryChina
- Language:Chinese
-
Abstract:
We report a case of an 18-year-old woman with systemic antibiotic anaphylaxis who presented anasarca and bilateral visual loss two weeks after the intravenous use of pazufloxacin. Ancillary fundus tests revealed bilateral cotton-wool spots, Purtscher flecken, edema, and retinal arteriolar occlusion around the optic disc. After pulse corticosteroid, administration of anti-anaphylactic agent, and general support therapy for one month, the patient showed a favorable change, with the symptoms lessened or free systemically, except the continuous aggravation of fundus ischemic change. After two intravitreal injections of Ranibizumab, there were still a large area of capillary non-perfusion and neovacularizations in the binocular retina, resulting in vitreous hemorrhage. The patient's visual acuity had still light perception after right-eye vitrectomy and presented no improvement during the postoperative follow-up of two years. Literature review revealed that there were many causes associated with Purtscher-like retinopathy, and the consequent visual impairment varied significantly. Prompt management of the underlying condition is crucial in giving the patient the best chance to restore vision.
