Risk factors analysis and security application discussion of Polygonum multiflorum based on retrospective study.
- Author:
Xiao-Xiao LAI
1
;
Jun-Biao WU
1
;
She CHEN
1
;
Ping LAI
1
;
Xiao-Hui WANG
1
;
Ying-Yan WANG
1
;
Yi-Ni LUO
1
;
Hua LIN
1
Author Information
- Publication Type:Journal Article
- Keywords: Polygonum multiflorum; application discussion; liver damage; risk factors
- From: China Journal of Chinese Materia Medica 2018;43(15):3205-3210
- CountryChina
- Language:Chinese
- Abstract: In recent years，hepatotoxicity problem of Polygonum multiflorum has caused high attention. Domestic scholars also explored the causes of liver damage caused by it. For example, the establishment of guideline for diagnosis and treatment of herb-induced liver injury, and the theory about relationship between hepatocyte toxicity and chemical composition, solvents, processing, use and pathological basis of patients and so on. To try to combine theory with practice，author analyzed risk factors about the case reports of P. multiflorum causing liver damage, and made some suggestions on P. multiflorum about individualized application, drug selection and requirements for taking. This for providing reference for the safe use of P. multiflorum.
