Detection of biofilms formation by electrochemical impedance spectroscopy.

Author: Lulu LIU ¹ ; Yi XU ¹ ; Renjie WANG ¹ ; Feiyun CUI ¹ ; Haitao LIU ¹ ; Li CHEN ¹
Author Information

1. School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400030, China.
Publication Type:Journal Article
Keywords: bacteria; biofilm; electrochemical impedance spectroscopy; microfluidic chip; quorum sensing
From: Chinese Journal of Biotechnology 2018;34(3):320-333
CountryChina
Language:Chinese
Abstract: Biofilms are microbial communities composed of bacteria cells and self-produced extracellular polymeric substances and lead to antibiotic resistance, forming a great threat in the fields of medicine, food industries and so on. The formation of biofilms is a multi-stage dynamic process regulated by multiple mechanisms. Recently, researchers paid much more attention to the related research areas of biofilms, especially the detection methods of biofilms. This paper introduced the characteristics and formation process of biofilms as well as the effects of quorum sensing on biofilms development. Meanwhile, we discussed the detection methods of biofilms, especially electrochemical impedance spectroscopy (EIS) in detection of biofilms in detail. Furthermore, we reviewed and predicted that microfluidic chips based EIS served as an in-situ and online monitoring method for biofilms growth.