Process in menstrual blood-derived mesenchymal stem cells for treatment of central nervous system diseases.

Mengmeng Liu; Xinran Cheng; Kaikai LI; Mingrui XU; Yongji WU; Mengli Wang; Qianru Zhang; Wenyong Yan; Chang Luo; Shanting Zhao

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Process in menstrual blood-derived mesenchymal stem cells for treatment of central nervous system diseases.

Author: Mengmeng LIU ¹ ; Xinran CHENG ¹ ; Kaikai LI ¹ ; Mingrui XU ² ; Yongji WU ¹ ; Mengli WANG ¹ ; Qianru ZHANG ¹ ; Wenyong YAN ¹ ; Chang LUO ³ ; Shanting ZHAO ¹
Author Information

1. Neurobiology Laboratory, College of Veterinary Medicine, Northwest A & F University, Yangling 712100, Shaanxi, China.
2. College of Food Science and Engineering, Northwest A & F University, Yangling 712100, Shaanxi, China.
3. Innovation Experimental College, Northwest A & F University, Yangling 712100, Shaanxi, China.
Publication Type:Journal Article
Keywords: central nervous system diseases; differentiation; menstrual blood-derived stem cells; repair; stem cell treatment
From: Chinese Journal of Biotechnology 2018;34(5):644-652
CountryChina
Language:Chinese
Abstract: Stem cell research has become a frontier in the field of life sciences, and provides an ideal model for exploring developmental biology problems such as embryogenesis, histiocytosis, and gene expression regulation, as well as opens up new doors for clinical tissue defective and inheritance diseases. Among them, menstrual blood-derived stem cells (MenSCs) are characterized by wide source, multi-directional differentiation potential, low immune rejection characteristics. Thus, MenSCs can achieve individual treatment and have the most advantage of the clinical application. The central nervous system, including brain and spinal cord, is susceptible to injury. And lethality and morbidity of them tops the list of all types of trauma. Compared to peripheral nervous system, recovery of central nervous system after damage remains extremely hard. However, the treatment of stem cells, especially MenSCs, is expected to solve this problem. Therefore, biological characteristics of MenSCs and their treatment in the respect of central nervous system diseases have been reviewed at home and abroad in recent years, so as to provide reference for the treatment of central nervous system diseases.