Progress in Research Drug Eluting Stents Drug-looding and Drug Release Kinetics.
10.3969/j.issn.1671-7104.2018.03.011
- VernacularTitle:药物洗脱支架载药及药物释放动力学研究进展
- Author:
Caixia SONG
1
;
Chao ZHOU
1
;
Haijun ZHANG
1
Author Information
1. National United Engineering Laboratory for Biomedical Material Modification, Dezhou, 251100. ##Email#.
- Publication Type:Journal Article
- Keywords:
coating method;
drug eluting stent;
release kinetics
- MeSH:
Drug Liberation;
Drug-Eluting Stents;
Kinetics;
Polymers;
Stents
- From:
Chinese Journal of Medical Instrumentation
2018;42(3):193-197
- CountryChina
- Language:Chinese
-
Abstract:
Drug eluting stents are one of the main devices of coronary intervention, which play a therapeutic role through the combination of medical devices. Drug is an important part of the drug eluting stents. The loading method, the type of carrier, drug and carrier interaction and the preparation process of the drug directly affect the drugs release kinetics characteristics of the device and the final treatment. According to the characteristics of the drug coating, drug coated stents can be divided into non-degradable polymers drug coated stents, biodegradable polymers drug coated stents and polymer-free drug eluting stents. This article discussed the stent coating process and drug release kinetics of the three types of drug eluting stent.
