Biomarkers for predicting the outcome of microdissection testicular sperm extraction for non-obstructive azoospermia patients: A systematic review.
- Author:
Yi-Chun WANG
1
;
Ya-Min WANG
1
;
Ning-Hong SONG
1
Author Information
1. Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
- Publication Type:Journal Article
- Keywords:
biomarker;
non-obstructive azoospermia;
male infertility
- MeSH:
Azoospermia;
Biomarkers;
analysis;
Humans;
Infertility, Male;
diagnosis;
Male;
Microdissection;
Retrospective Studies;
Sperm Retrieval;
Spermatozoa;
Testis
- From:
National Journal of Andrology
2018;24(3):263-267
- CountryChina
- Language:Chinese
-
Abstract:
Infertility is a common medical condition which affects nearly 15% of the world population. Non-obstructive azoospermia (NOA) is a most challenging problem inducing male infertility and does not respond to the existing medication. Surgery is the primary method for obtaining sperm from NOA patients, but the outcome of testicular sperm extraction is unpredictable preoperatively. Recently, with the development of detection techniques for male infertility, some new biomarkers have come into notice, which may be of some value in predicting the outcome of microdissection testicular sperm extraction (MTSE) and evaluating male infertility. This article presents an overview of the known biomarkers contributive to the prediction of the outcome of MTSE for NOA patients.