Metabolic complications of androgen deprivation therapy and its intervention management.
- Author:
Yong-Hui HU
1
;
Song WU
2
;
Meng ZHANG
3
Author Information
1. Department of Endocrinology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.
2. Department of Urology， Shenzhen Luohu People＇s Hospital， Shenzhen Following Precision Medical Ｒesearch Institute， Shenzhen， Guangdong 518001 ， China.
3. Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230031, China.
- Publication Type:Journal Article
- Keywords:
androgen deprivation therapy;
intervention management;
metabolic complication;
prostate cancer
- MeSH:
Androgen Antagonists;
adverse effects;
Blood Glucose;
drug effects;
Body Composition;
drug effects;
Cardiovascular System;
drug effects;
Cholesterol;
blood;
Humans;
Male;
Prostatic Neoplasms;
blood;
drug therapy
- From:National Journal of Andrology
2018;24(3):277-281
- CountryChina
- Language:Chinese
-
Abstract:
Androgen deprivation therapy (ADT) is one of the dominant treatment options for advanced prostate cancer, which has been certified to significantly improve the overall survival of prostate cancer patients. However, it sometimes can also produce severe adverse effects on body metabolism. This review summarizes the adverse effects of ADT on body composition, the levels of cholesterol and blood glucose, and the cardiovascular system, and the intervention management of these metabolic complications as well.
