Current progress in single sperm cryopreservation.
- Author:
Jian-Wen HOU
1
;
Xiang-Qian MENG
1
;
Ying ZHONG
1
Author Information
1. Center of Reproductive Medicine, Maternity and Child Health Hospital of Jinjiang District, Chengdu, Sichuan 610051, China .
- Publication Type:Journal Article
- Keywords:
empty zona pellucida;
micro drop;
testicular sperm;
single sperm cryopreservation
- MeSH:
Azoospermia;
therapy;
Cryopreservation;
methods;
Heterozygote;
Humans;
Male;
Oligospermia;
therapy;
Reproduction;
Semen Preservation;
methods;
Spermatozoa
- From:
National Journal of Andrology
2018;24(5):447-451
- CountryChina
- Language:Chinese
-
Abstract:
Sperm cryopreservation has been widely used in assisted reproduction, but conventional techniques are not suitable for the cryopreservation of small numbers of sperm. The application of the single sperm cryopreservation technique has significantly improved the clinical treatment of cryptozoospermia and non-obstructive azoospermia. Ever since Cohen et al first developed the method of single sperm cryopreservation in 1997, constant efforts have been made to develop the carriers for this technique. In this review, we mainly discuss the existing methods and clinical outcomes of single sperm cryopreservation.
