Features and management of very early onset inflammatory bowel disease.
- Author:
Jie-Yu YOU
1
,
2
Author Information
1. Department of Gastroenterology, Hunan Children&prime
2. s Hospital, Changsha 410000, China. yjy6601@sina.com.
- Publication Type:Journal Article
- MeSH:
Humans;
Inflammatory Bowel Diseases;
etiology;
therapy;
Nutritional Support;
Stem Cell Transplantation
- From:
Chinese Journal of Contemporary Pediatrics
2018;20(5):341-345
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD) is a chronic nonspecific intestinal inflammatory disease of unknown etiology. This disease includes three main types: Crohn′s disease (CD), ulcerative colitis (UC), and IBD-unclassified (IBD-U). IBD is frequently presented in adults, but in recent years, there is a rising incidence in pediatric populations. Very early onset IBD (VEO-IBD) is a fraction of pediatric IBD, but they have exclusive phenotypic and genetic characteristics such that they are accompanied by severe disease course and resistance to conventional therapy. The purpose of this review is to provide a contemporary overview of the clinical features, pathogenesis, and management of VEO-IBD.
