Recent Advances in Immunotherapy of Lung Cancer.

Author: Cristina ICLOZAN ¹ ; Dmitry I GABRILOVICH
Author Information

1. Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL, USA. dmitry.gabrilovich@moffitt.org
Publication Type:Review
Keywords: Lung neoplasms; Immunotherapy; Translational medical research; Combination modality therapy; Vaccines; Immunomodulation
MeSH: Immune System; Immunomodulation; Immunotherapy; Lung; Lung Neoplasms; Translational Medical Research; Vaccines
From:Journal of Lung Cancer 2012;11(1):1-11
CountryRepublic of Korea
Language:English
Abstract: Immunotherapy was long considered as an attractive modality in the treatment of lung cancer. However, clinical successes were hampered by the inability to achieve potent activation of the antitumor immune system and effectively overcome the immune suppressive environment associated with lung cancer. Recent advances in cancer immunotherapy demonstrate that these limitations can be surmounted. In this review, we discuss the recent advances in immunotherapy of lung cancer and their potential implication for management of this disease.