Incidence of Bone Marrow Involvement in Different Pathological Type Lymphoma Patients.
- Author:
Qing CHEN
1
,
2
;
Lu-Ting ZHU
3
;
Xi-Nan CEN
4
;
Ze-Yin LIANG
3
;
Jin-Ping OU
3
;
Li-Hong WANG
3
;
Wen-Sheng WANG
3
;
Wei LIU
3
;
Zhi-Xiang QIU
3
;
Yu-Jun DONG
3
;
Mang-Ju WANG
3
;
Yu-Hua SUN
3
;
Yue YIN
3
;
Qian WANG
3
;
Han-Yun REN
3
Author Information
- Publication Type:Journal Article
- MeSH: Biopsy; Bone Marrow; Fluorodeoxyglucose F18; Humans; Incidence; Lymphoma; Positron Emission Tomography Computed Tomography; Retrospective Studies
- From: Journal of Experimental Hematology 2018;26(3):765-771
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the incidence of bone marrow involvement in patients with different pathological types of lymphoma.
METHODSThe results of bone marrow tests including bone marrow aspiration(BMA), flow cytometry detection, bone marrow biopsy(BMB) and F-FDG PET/CT, were analyzed retrospectively in 702 cases of newly diagnosed lymphoma with bone marrow assessment in our hospital from October 2000 to September 2016. If one of the above-mentioned 4 tests showed positive, the lymphoma patient was judged as bone marrow involved.
RESULTSThe incidence of bone marrow involvement (BMI ) in the patients with NHL was much higher than that in patients with HL [32.6 %(201/616) vs 15%(13/86)](P<0.05). For patients with NHL, the incidence of bone marrow involvement in B-cell lymphoma was higher than that in T-cell lymphoma (37.0% vs 22.6%)(P<0.05). According to different pathological types, the incidences of BMI in the patient with mantle cell lymphoma, hepatosplenic T-cell lymphoma, diffuse large B-cell lymphoma (DLBCL) and follical lymphoma (FL) were 88% (25/22), 100% (5/5), 21.8% (56/257), and 38.5% (15/39) , respectively.
CONCLUSIONThe incidence of bone marrow involvement varies in different pathological types of lymphoma.Bone marrow assessment has significant importance for stading of newly diagnosed lymphoma patients.
