Improvement Effects of Drink Containing Ampelopsis glandulosa Extract on Knee Joint Discomfort
- VernacularTitle:Improvement Effects of Drink Containing Ampelopsis glandulosa Extract on Knee Joint Discomfort
- Author:
Tomohiro MATSUMOTO
1
;
Akiko WATANABE
1
;
Hiroshi TAKAGI
1
;
Seiji HASEGAWA
1
;
Satoru NAKATA
1
;
Hiroyuki TANAKA
2
Author Information
- Keywords: joint disease; hyaluronic acid; arthritis; discomfort of knee joint; Ampelopsis glandulosa extract
- From:Japanese Journal of Complementary and Alternative Medicine 2018;15(1):9-14
- CountryJapan
- Language:Japanese
- Abstract: The prevalence of joint diseases in Japan is increasing yearly and it causes the need of nursing care and reduces quality of life. Therefore, there is an urgent need for the development of approaches to prevent and treat the diseases. In the present study, we investigated the effective, healthy food material focusing on the metabolism of joint cartilage. Ampelopsis glandulosa (A. g. ) extract improved exacerbation of hyaluronic acid metabolism and NFκB nuclear translocation caused by inflammatory cytokines, and it suppressed the onset of collagen-induced arthritis in mice. Moreover, intake of the drink containing A. g. extract for three months improved discomfort, pain, and bending angle of knee joint in activities of daily living. These results suggest that A. g. extract improves hyaluronic acid metabolism of joint cartilage, and it is expected to prevent and improve joint disease by long-term intake of the drink containing A. g. extract.
