A Case of Brain Edema Caused by Radiation Necrosis After Stereotactic Radiosurgery Treated with Saireito
- VernacularTitle:定位放射線治療後の放射線脳壊死の周辺浮腫に柴苓湯が有効であった1例
- Author:
Yoshinao HARADA
1
;
Kouzou MATSUMURA
2
;
Hajime ARAI
2
Author Information
- Keywords: radiation necrosis; brain edema; metastatic brain tumor; saireito
- From:Kampo Medicine 2018;69(2):140-144
- CountryJapan
- Language:Japanese
- Abstract: A 60-year-old female patient was treated with gamma knife on the left frontal lobe metastatic brain tumor. After 3 months, the tumor and peri-focal edema turned worse due to radiation necrosis. Despite increasing doses of steroid administration, the deterioration lasted for 6 months. The symptoms and brain edema did not improve for over a year, but we decided to observe the patient without bevacizumab. We performed Methionine-PET to diagnose radiation necrosis of the brain, and confirmed absence of hot spots. The steroid therapy continued and added saireito 9 g/day, because we thought brain edema was concerned with fluid retention. After 9 months, head MRI showed improvements of the brain edema. Saireito may help improve brain edema due to radiation necrosis.
