End-stage Treatment of a Patient with Progressive Supranuclear Palsy and Severe Retroflexion of the Neck -Improvement in Retroflexion of the Neck by Botulinum Therapy: A Case Report-
10.14442/generalist.41.125
- VernacularTitle:高度の頸部後屈を呈した晩期の進行性核上性麻痺患者への治療―ボツリヌス療法が頸部後屈に奏功した1例―
- Author:
Masahiro HAYASHI
;
Katsuji KOBAYASHI
- Keywords:
botulinum therapy;
cervical dystonia;
muscle tone;
analgistic effects;
progressive supranuclear palsy
- From:An Official Journal of the Japan Primary Care Association
2018;41(3):125-128
- CountryJapan
- Language:Japanese
-
Abstract:
Progressive supranuclear palsy (PSP) comprises psychiatric, neurological and physical complications. In the late stage, most patients with PSP are bed-bound because of motor disability. PSP manifests as predominantly axial abnormality in posture and abnormal muscle tone, resulting in cervical retroflexion and somatic pains. Severe retroflexion of the neck is frequently a cause of repeated aspiration pneumonia that affects survival expectancy. We injected botulinum toxin (BTX) for severe retroflexion using a CT-guided procedure to confirm the anatomical locations of paravertebral muscles and to localize the paravertebral target muscles for a patient with PSP who had repeated pneumonia caused by retroflexion-related dysphagia. BTX injection treatment markedly ameliorated the cervical dystonia and concomitant dysphagia. The patient has recovered and may be able to be discharged to home. There are few reports on the BTX injection technique, but BTX has analgesic effects and induces relaxation of abnormal muscle tension. Therefore, it may be applicable to other movement disorders at the late stage.
