Pharmacokinetics and drug safety of oral infectious disease during pregnancy.

VernacularTitle:妊娠期药物动力学及口腔感染性疾病的安全用药
Author: Hong-Yu LI ¹ ; Ya-Chuan ZHOU ¹ ; Xue-Dong ZHOU ¹ ; Li-Wei ZHENG ¹
Author Information

1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Publication Type:Journal Article
Keywords: medication; oral health; pharmacokinetics; pregnancy
From: West China Journal of Stomatology 2018;36(3):319-324
CountryChina
Language:Chinese
Abstract: Pregnancy is a time of particular vulnerability in terms of physiologic changes resulting in higher risk of oral infectious diseases. There is emerging evidence showing that irrational dental treatment and drug therapy are associated with adverse pregnancy outcomes, including infant malformation or spontaneous abortion. This article reviews the pharmacokinetics of medications in pregnant women and the fetus and introduces a guideline for drug therapy and common dental drugs used during pregnancy.