- VernacularTitle:唾液蛋白质糖基化及其与全身和口腔疾病关系的研究进展
- Author:
Rui MA
1
;
Xian PENG
1
;
Yi XU
1
;
Ding-Yu DUAN
1
Author Information
- Publication Type:Journal Article
- Keywords: glycosylation; oral diseases; protein post-translational modification; saliva; systemic diseases
- From: West China Journal of Stomatology 2018;36(3):336-341
- CountryChina
- Language:Chinese
- Abstract: Protein glycosylation is one of the most important protein post-translational modifications that can affect life activities by endowing the protein with various structural and functional features. Saliva is an easy-to-obtain, noninvasive body fluid that contains components originating from serum, gingival crevicular fluid, and oropharyngeal mucosae. In recent years, understanding of saliva has been constantly updated with the developments in related research. Studies have shown that salivary proteins can be used as diagnostic markers for certain diseases, and changes of protein glycosylation in saliva are generally considered to be related to many diseases. In this review, salivary protein glycosylation and its relationship with systemic and oral diseases were discussed.