Intestinal Microbiota and Kidney Diseases.
10.1007/s11655-017-2927-5
- Author:
Ao XIE
1
;
Jie SHENG
1
;
Feng ZHENG
2
Author Information
1. Advanced Institute for Medical Science, The Second Hosptial, Dalian Medical University, Dalian, Liaoning Province, 116044, China.
2. Advanced Institute for Medical Science, The Second Hosptial, Dalian Medical University, Dalian, Liaoning Province, 116044, China. zheng-feng@dmu.edu.cn.
- Publication Type:Journal Article
- Keywords:
IgA nephropathy;
chronic kidney disease;
microbiota;
uremia
- MeSH:
Gastrointestinal Microbiome;
Humans;
Kidney Diseases;
microbiology
- From:
Chinese journal of integrative medicine
2018;24(6):406-408
- CountryChina
- Language:English
-
Abstract:
Kidney diseases are common and the incidence rate is increasing. Gut microbiota is involved in metabolic and immune regulation of the host. Genetic, alimentary and environmental disease factors may change gut flora and increase opportunistic and pathogenic bacteria, contributing to immune or non-immune mediated kidney diseases including IgA nephropathy and diabetic nephropathy. Additionally, bacterial metabolites may be a source of uremic toxins. Thus, identification of diversity, composition, and metabolic and immunologic features of gut bacteria in chronic kidney diseases may help understand pathogenetic mechanism and develop therapy for diseases.
