Multiple risk factors prediction models for high risk population of colorectal cancer.
- Author:
Xiyi JIANG
1
;
Lu LI
2
;
Huijuan TANG
1
;
Tianhui CHEN
1
Author Information
1. Group of Molecular Epidemiology & Cancer Precision Prevention, Institute of Occupational Diseases, Zhejiang Academy of Medical Sciences, Hangzhou 310013, China.
2. School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
- Publication Type:Journal Article
- MeSH:
Asian Continental Ancestry Group;
Case-Control Studies;
Cohort Studies;
Colorectal Neoplasms;
Humans;
Incidence;
Risk Assessment;
Risk Factors
- From:
Journal of Zhejiang University. Medical sciences
2018;47(2):194-200
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is caused by the interaction of genetic and environment factors. Domestic and foreign scholars have attempted to develop several colorectal cancer risk prediction models, in order to identity risk factors, to screen for high risk population and evaluate the risk of developing colorectal cancer, so as to provide personalized screening protocols for individuals with different risk, and eventually reduce the incidence and mortality rate of colorectal cancer. Currently, the common colorectal cancer risk prediction models were mainly developed based on case-control study and cohort study. Models developed in European and American regions and Asia (excluding China) only include common risk factors, while Chinese models also include hereditary factors on the bases of common risk factors. However, the development and verification of each model are mainly based on local population, whether it can be applied for other population need to be determined. This article reviews the development, validation and evaluation of the risk prediction models, in order to provide a basis for developing more precise risk prediction models for colorectal cancer.
