Research progress on exosomes in diagnosis and treatment of cardiovascular diseases.
- Author:
Fushan LI
1
;
Ran FANG
1
;
Lin RAO
1
;
Feilong MENG
1
;
Xiaoli ZHAO
1
Author Information
1. College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
- Publication Type:Journal Article
- From:
Journal of Zhejiang University. Medical sciences
2018;47(3):320-326
- CountryChina
- Language:Chinese
-
Abstract:
Exosome is a specific subset of vesicles from intracellular origin vesicles containing varies of microRNAs, mRNAs, proteins and lipids. It has been demonstrated that contents of exosomes could be altered due to different physiological and pathological stress, which could be used as clinical biomarker to reveal the disease state. In addition, according to previous studies, exosomes could exert protective roles for cardiovascular diseases such as atherosclerosis, myocardial infarction and ischemia/reperfusion injury, etc. The aim of this review is to summarize current research progress on exosomes, related implications in diagnosis and treatment of cardiovascular diseases and corresponding mechanisms.
