Customization of enzyme molecular machine and cell factory, leading the future of biomanufacturing industry.

Author: Shuiqin JIANG ¹ ; Dongzhi WEI ¹
Author Information

1. State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, School of Biotechnology, East China University of Science and Technology, Shanghai 200237, China.
Publication Type:Journal Article
Keywords: biomanufacturing; catalysts customization; cell factory; enzyme molecular machine; industry development
From: Chinese Journal of Biotechnology 2018;34(7):1024-1032
CountryChina
Language:Chinese
Abstract: The development and application of industrial enzymes have penetrated major industrial fields. China faces a major challenge as a large country in applying enzyme but a small one in producing enzyme. Biocatalysis has become an important technology and strategy of industrial development in the world since chemical catalysis encounters the crises from resource, energy and environment. The application of efficient and clean biocatalysis is one of the important ways to realize the sustainable development of chemical industry and to modernize the fermentation industry. From perspective of the industry-university-research cooperation, we reviewed the current status and the future development of enzyme engineering from the aspects of enzyme resources, customization of enzyme molecular machine and cell factory.