The preliminary study on biomechanical properties of four synthetic implants for reconstructive surgery of pelvic floor dysfunction.
10.7507/1001-5515.201707071
- Author:
Yali MIAO
1
;
Jirui WEN
2
;
Shichao WANG
2
;
Zhiwei ZHAO
2
;
Jiang WU
3
Author Information
1. West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Disease of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, P.R.China.
2. School of West China Basic Medicine and Forensic Medicine, Sichuan University, Chengdu 610041, P.R.China.
3. School of West China Basic Medicine and Forensic Medicine, Sichuan University, Chengdu 610041, P.R.China.jw@scu.edu.cn.
- Publication Type:Journal Article
- Keywords:
biomechanics;
maximum elongation;
maximum load;
modulus of elasticity;
reconstructive surgery of pelvic floor dysfunction;
synthetic implants;
ultimate stress strength
- From:
Journal of Biomedical Engineering
2018;35(3):409-414
- CountryChina
- Language:Chinese
-
Abstract:
This study aimed to investigate biomechanical properties of synthetic implants for reconstructive surgery of pelvic floor dysfunction. In this dissertation, we chose four synthetic implants, i.e. total pelvic floor repair system (PROLIFT), gynecone TVT obtutator system (TVT-O), intra-vaginal sling placement device (IVS) and acellular dermal matrix (Renov), for tensile test respectively. The biomechanical properties of four synthetic implants were measured and analyzed using a material testing machine (Instron 4302 versatile material testing machine). The biomechanical parameters included ultimate stress strength, modulus of elasticity, maximum load and maximum elongation. The results showed that the maximum load of the four symthetic implants was TVT-O > IVS > PROLIFT > Renov, and the maximum load of TVT-O was significantly higher than PROLIFT and Renov ( < 0.05). The ultimate stress strength was TVT-O > IVS > PROLIFT > Renov, with no significant differences among them ( > 0.05). The maximum elongation of the four implants was TVT-O > PROLIFT > IVS > Renov, and the maximum elongation of TVT-O and PROLIFT were both significantly higher than Renov ( < 0.05). The modulus of elasticity was IVS > Renov > TVT-O > PROLIFT, with no significant differences among them ( > 0.05). Taken together, the present study demonstrates that the modulus of elasticity of IVS was the highest in the four synthetic implants; TVT-O had the highest mechanical strength; The maximum load, ultimate stress strength and maximum elongation of Renov were all the lowest; The mechanical properties of PROLIFT was the most stable, and its modulus of elasticity was the lowest in the four synthetic implants, which had good extensibility and elasticity. Therefore, it is necessary to pay attention to the biomechanical properties of new pelvic reconstructive materials for the clinical pelvic reconstructive surgery.
