Thoughts of omics research on quality formation in Dao-di herbs.
- Author:
Cheng-Cheng WANG
1
;
Hui ZHAO
1
;
Ying YAN
1
;
Jing-Jing SHI
1
;
Shu-Yu CHEN
1
;
Meng-Xia TAN
1
;
Jia-Li CHEN
1
;
Zi-Xiu LIU
1
;
Cui-Hua CHEN
1
;
Li-Si ZOU
1
;
Xun-Hong LIU
1
Author Information
- Publication Type:Journal Article
- Keywords: Dao-di herbs; biosynthetic pathway; genetic inheritance; omics; quality formation
- From: China Journal of Chinese Materia Medica 2018;43(11):2407-2412
- CountryChina
- Language:Chinese
- Abstract: Dao-di herbs have been recognized as "quality models" with a firmly stable status. The formation of Dao-di herbs quality is involved from the genetic inheritance on the molecular level to the metabolic phenotype of final products, and the full material-based biosynthetic pathway remains unknown. In recent years, an increasing variety of omics technologies has provided new methods and ideas for the analysis of complex life systems and are suitable for explanation of quality formation in Dao-di herbs as well. In order to alleviate the scarcity of natural resources and offer scientific guidance of transplanting varieties, achievements of omics in the aspects of Dao-di herbs from genetics to phenotyping, the biosynthetic pathway of secondary metabolites, the interaction with human body and the new methods of quality evaluation have been summarized. It will be a fundamental work for protection and utilization of Chinese medicine resources.
