Study on geographical variation of medicinal ingredients contents in Scutellaria baicalensis from different provenances.
10.19540/j.cnki.cjcmm.20180510.009
- Author:
Yong-Jie LI
1
;
Rong-Xiu LIU
1
;
Wen-Cang TIAN
1
;
Xue-Sen WANG
1
;
Zhi-Yan HOU
1
;
Lei MENG
1
;
Guo-Hu SONG
2
;
Xue-Wen ZHANG
2
;
Sheng-Li WEI
1
Author Information
1. College of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
2. Chengde Pharmaceutical Co., Ltd.， Affiliated to China National Pharmaceutical Corporation， Chengde 067000， China.
- Publication Type:Journal Article
- Keywords:
Scutellaria baicalensis;
baicalin;
geographical variation;
provenance selection
- From:
China Journal of Chinese Materia Medica
2018;43(13):2664-2669
- CountryChina
- Language:Chinese
-
Abstract:
In order to investigate the genetic difference on medicinal components of Scutellaria baicalensis from different provenances on the genetic difference, the S. baicalensis provenance tests were arranged by randomized block design.Excavating the crude drugs that have been growing for three years, with the same drying process, the content of baicalin, baicalein, wogonoside, wogonin and laminarin A in S. baicalensis were detected by HPLC, and then the data were analyzed. The results indicated that the content of baicalin in different provenances of S. baicalensis was significantly different (<0.05), while the variation of baicalein reached extremely significant level (<0.01). Cluster analysis showed that if the distance was divided by 5.0, the provenances in Chengde, Hebei province were divided into two independent populations, while the other two populations had large geographic spans. The results show that the significant geographical variations exist in the content of medicinal components in S. baicalensis. The study laid a theoretical foundation of provenance selection of S. baicalensis.
