Morphological, microscopic, multiple-component assay and fingerprinting based systematic research on quality evaluation of Moutan Cortex(Paeonia suffruticosa).
10.19540/j.cnki.cjcmm.20180510.002
- Author:
Zhi-Qiang WANG
1
;
Yong CHEN
1
;
Shuang-Shuang LIU
2
;
Hong-Xiang LI
2
;
Wei-Wen LI
3
;
Ling DONG
3
;
Chun-Nian HE
2
;
Fei-Hu CHEN
1
;
Pei-Gen XIAO
2
Author Information
1. School of Pharmacy, Anhui Medical University, Hefei 230032, China.
2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
3. Horticultural Research Institute of Anhui Academy of Agricultural Sciences, Hefei 230031, China.
- Publication Type:Journal Article
- Keywords:
Moutan Cortex;
UHPLC;
growth rings;
morphological;
quality evaluation
- From:
China Journal of Chinese Materia Medica
2018;43(14):2899-2907
- CountryChina
- Language:Chinese
-
Abstract:
The purpose of this study was to combine morphological, microscopic, UHPLC multiple-component assay and fingerprinting studies in order to evaluate the quality of Moutan Cortex (MC) systematically. The root system of Paeonia suffruticosa was measured to compare the morphological variation and the chemical composition of different grades of MC was discussed according to previous studies. The difference between the main microscopic features of MC powder and the xylem powder is dramatic, the MC powder contains great amount of starch granules and clusters of calcium oxalate, while the xylem powder displays considerable vessels. Interestingly, the growth rings of P. suffruticosa was first reported in the xylem of the root transection, this can help to determine the growth years of the plant. Moreover, through the assay of 16 component, MC produced in Tongling and Bozhou in Anhui province were compared, content of PGG in MC produced in Bozhou was significantly higher than MC produced in Tongling (<0.01). MC with different growth years, MC with xylem and unprocessed MC and MC decoction pieces were compared respectively by combining the results of 16 compounds assay and fingerprinting. It is proposed that the quality evaluation standard include the assay of paeoniflorin. Above all, the holistic quality difference can be evaluated more comprehensively by combining multiple analytical methods.
