Chemical constituents from roots of Viburnum setigerum.
10.19540/j.cnki.cjcmm.20180315.001
- Author:
Yuan GAO
1
;
Li-Sha ZHANG
1
;
Jian GE
1
;
Yi-Hang WU
1
;
Zhen-Bao JIA
1
;
Yong-Yong ZHANG
1
;
Jia-Rong PAN
1
Author Information
1. College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
- Publication Type:Journal Article
- Keywords:
Caprifoliaceae;
Viburnum setigerum;
chemical constituents;
lignan
- From:
China Journal of Chinese Materia Medica
2018;43(14):2950-2955
- CountryChina
- Language:Chinese
-
Abstract:
This experiment was to study the constituents of the roots of Viburnum setigerum through various column chromatographic techniques. Thirteen compounds were obtained and their structures were identified using chemical and spectroscopic methods as (7αH, 8'αH)-4, 4', 8α-trihydroxy-3, 3', 9-trimethoxy-7, 9'-epoxylignan (1), (7αH, 8'αH)-4, 4', 8α, 9-tetrahydroxy-3, 3'-dimethoxy-7, 9'-epoxylignan (2), alashinol G (3), alashinol F (4), (-)-secoisolariciresinol (5), (7R, 7'R, 8R, 8'S)-3, 3'-dimethoxy-7, 7'-epoxylignane -4, 4', 9, 9'-tetraol (6), (7αH, 8αH, 8'βH)-4, 4', 7'α, 9-tetrahydroxy-3, 3'-dimethoxy-7, 9'-epoxylignan (7), loganin (8), dihydroquercetin (9), protocatechuic acid (10), 4-hydroxy-3-methoxy-benzoic acid (11), adoxoside (12), and catechin (13). Compound 1 was a new compound. Compounds 3-7 and 11 were reported from the genus Viburnum for the first time. All compounds were separated from this plant for the first time.