Advances in studies on steroidal saponins and their pharmacological activities in genus Lilium.
10.19540/j.cnki.cjcmm.2018.0055
- Author:
Lin-Ming LUO
1
;
Li QIN
1
;
Gang PEI
1
;
Shao-Guo HUANG
1
;
Xiao-Jiang ZHOU
1
;
Nai-Hong CHEN
1
Author Information
1. College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.
- Publication Type:Journal Article
- Keywords:
bulbs;
genus Lilium;
pharmacological activities;
steroidal saponins
- From:
China Journal of Chinese Materia Medica
2018;43(7):1416-1426
- CountryChina
- Language:Chinese
-
Abstract:
Genus Lilium plants contain a variety of steroidal saponins, so far at least 82 steroidal saponins have been found in the bulbs of Lilium species, including 13 spirostanol saponins (1-13), 39 isospirostanol saponins (14-52), 7 pseudospirostanol saponins (53-59), and 23 furostanol saponins (60-82). Studies have showed that these steroidal saponins exhibit a wide range of pharmacological activities, including antitumor, antibacterial, antiinflammatory, antioxidant, antidepressant, hepatoprotective, hypoglycemic, sedative-hypnotic effect, and inhibition of cAMP phosphodiesterase and Na⁺-K⁺ ATP, et al. This paper has classified and summarized the 82 steroidal saponins isolated and identified from the bulbs of Lilium species and their correlative biological activities. Also, their structural characteristics and structure-activities relationship have been discussed, which could provide references for further research and application development of Lilium plants.
