Study the effectiveness of Morinda Officinalis How (MOH) on the Genital Organs of Male Rats
- Author:
Quan Manh Nguyen
;
Huong Thi Giang Nguyen Tran
- Publication Type:Journal Article
- Keywords:
Morinda officinalis How;
Genital organs;
Male rat
- MeSH:
Morinda officinalis How;
Genital organs;
Male rat
- From:Journal of Medical Research
2008;0(1):77-84
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Introduction: To date, there has not been any systematical and experimental research aimed at indicating the effects of Morinda officinalis How on the genital organs of male rats. \r\n', u"Objectives: To determine the effectiveness of Morinda officinalis How (MOl-I) on the genital organs of male rats, to describe the changes in histology of testicles, and evaluate the testosterone concentration in mature male rats' bloods when dosed with MOH.\r\n", u'Subjects and method: Mature and immature rats were divided into 3 groups: mature rats, castrated and non - castrated immature rats. The rats have a daily dosage of MOH: 20g/kg. The above groups of rats were euthanized after 10 days; their testicles, seminal vesicles, prostates and Cowper land were weighed; specimens of histology of testicles were made; testosterone concentration in the bloods of the mature rats was measured. Results were compared amongst experimental groups. \r\n', u'Results and conclusion: Compared with the control group, MOH (dosage 20g/kg) increased the weight of testicles, seminal vesicles, prostates, and Cowper lands (p < 0.05). In mature rats, MOH increased the testosterone concentration in the blood in comparison with the control group (p < 0.05). MOH did not change the histology of testicles, diameter of seminal ducts, but it did change the rate of seminal ducts having sperm compared with the control group and the testosterone injected group (p < 0.05). \r\n', u'
