N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE AND METABOLIC RISK FACTORS
- VernacularTitle:НАТРИ ХӨӨГЧ ПЕПТИД БА БОДИСЫН СОЛИЛЦООНЫ ЭРСДЭЛТ ХҮЧИН ЗҮЙЛС
- Author:
Mijidsuren G
1
;
Chingerel Kh
1
;
Tsolmon U
1
Author Information
1. MNUMS, School of Medicine, Department of Internal Medicine-I
- Publication Type:Journal Article
- Keywords:
Chronic heart failure, NT-pro BNP, screening, metabolic risk factors.
- From:Innovation
2018;12(4):4-7
- CountryMongolia
- Language:Mongolian
-
Abstract:
BACKGROUND. Heart failure is public health burden in developed countries. There are currently
6.5 million adults in the US who heart failure and this number is expected to rise to more than
8 million people by 2030. AHA and ESC recommend natriuretic peptide biomarker-based
screening and interventions aimed at modifying risk factors for patients at risk of developing
heart failure as these can be useful in prevention of left ventricular dysfunction or new onset
heart failure.
OBJECTIVE: To investigate the level of NT-proBNP and its association with metabolic risk factors
and possible early detection of chronic heart failure in general population.
MATERIAL AND METHODS. In the study, 194 participants aged from 35 to 65 were enrolled.
We measured metabolic risk factors and level of NT-proBNP of participants. The two group
of participants who have positive and negative NT-proBNP results were compared by the
metabolic risk factors.
RESULTS. NT-proBNP results were positive in 16.49% (n=32) of the participants. The mean values of
age, frequencies of hypertension, systolic and diastolic blood pressure significantly increased
in participants with positive NT-proBNP results, while mean values of BMI, frequencies of
diabetes, total cholesterol and LDL decreased in participants with negative NT-pro BNP results.
CONCLUSION: NT-proBNP was positively related to age, arterial hypertension, sistolic and
diastolic blood pressure and inversely related to body mass index, obesity, diabetes,
cholesterol, LDL.BACKGROUND. Heart failure is public health burden in developed countries. There are currently
6.5 million adults in the US who heart failure and this number is expected to rise to more than
8 million people by 2030. AHA and ESC recommend natriuretic peptide biomarker-based
screening and interventions aimed at modifying risk factors for patients at risk of developing
heart failure as these can be useful in prevention of left ventricular dysfunction or new onset
heart failure.
OBJECTIVE: To investigate the level of NT-proBNP and its association with metabolic risk factors
and possible early detection of chronic heart failure in general population.
MATERIAL AND METHODS. In the study, 194 participants aged from 35 to 65 were enrolled.
We measured metabolic risk factors and level of NT-proBNP of participants. The two group
of participants who have positive and negative NT-proBNP results were compared by the
metabolic risk factors.
RESULTS. NT-proBNP results were positive in 16.49% (n=32) of the participants. The mean values of
age, frequencies of hypertension, systolic and diastolic blood pressure significantly increased
in participants with positive NT-proBNP results, while mean values of BMI, frequencies of
diabetes, total cholesterol and LDL decreased in participants with negative NT-pro BNP results.
CONCLUSION: NT-proBNP was positively related to age, arterial hypertension, sistolic and
diastolic blood pressure and inversely related to body mass index, obesity, diabetes,
cholesterol, LDL.
