TWO YEARS SURVIVAL IN PATIENTS WITH STEMI TREATED PRIMARY PCI
- VernacularTitle:ЗҮРХНИЙ ЦОЧМОГ ШИГДЭЭСТЭЙ ТСДЭ ХИЙГДСЭН ӨВЧТӨНИЙ 2 ЖИЛ ДОТОРХ АМЬДРАХ ЧАДВАРЫН СУДАЛГАА
- Author:
Batmyagmar Kh
1
;
Surenjav Ch
2
;
Amarjargal B
3
;
Narantuya D
4
Author Information
1. TSCH, DoA
2. SSCH
3. UPS
4. TSCH DoMI, MAPH
- Publication Type:Journal Article
- Keywords:
Acute myocardial infarction (AMI), percutaneous coronary intervention (PCI), thrombolysis in myocardial infarction (TIMI), left ventricular global longitudinal strain (LVGLS)
- From:Innovation
2018;12(4):18-21
- CountryMongolia
- Language:Mongolian
-
Abstract:
BACKGROUND: Acute myocardial infarction is leading cause of global morbidity and mortality and major health care burden in worldwide.
Previous studies demonstrated that restoration of myocardial tissue perfusion after primary PCI is significant factor of improved outcome.
In Mongolia, studying long term effects of primary PCI in patients with AMI and its’ association with coronary blood flow, tissue Doppler imaging, left ventricular global strain pattern in speckle-tracking echocardiography and risk factors are essential in theoretical and clinical practice.
AIMS: To determine long term effects of primary PCI in patients with AMI and its’ association with left ventricular strain pattern in speckle-tracking echocardiography, risk factors and patient prognosis.
METHODS: We used prospective cohort study design. We were selected 414 patients with AMI who treated by primary PCI between 2015 and 2016 at the State Third Central Hospital. Echocardiographic examination was conducted on Philips iE33 xMATRIX ultrasound machine. The PCI was performed according to the MNS:6379-2013 standard.
RESULTS: Mean age was 60±13 and majority of them were male 84% (n=347). Complete coronary perfusion (TIMI-3) was achieved in patients 88% (n=367) after primary PCI.
There was weak, negative correlation between coronary TIMI flow grade and left ventricular global longitudinal strain (r=-0.183, CI 95% -0.289 to-0.066, p<0.001). In patients with incomplete coronary perfusion (TIMI<3), mortality rate was significantly higher during 24 months follow-up.
After primary PCI, 24 months mortality was 9.9% (n=39). Cut-off value of left ventricular global longitudinal strain which predict long term (within 24 month follow-up) mortality was -12.93% (sensitivity 74.4%, specificity 74.3%). Mortality during 24 months follow-up was significantly different between left ventricular global longitudinal strain groups (log-rank test p<0.001) and mortality was higher in left ventricular global longitudinal strain ≥ -12.93% group.
CONCLUSION: Coronary no-reflow phenomenon is associated with long term mortality in patients with AMI. In patients with AMI who treated by PCI, long term mortality is predictable with left ventricular global longitudinal (≥-12.93%, p<0.001) strain.
