Annual Report on External Quality Assessment in Diagnostic Genetics in Korea (2004).
- Author:
Sun Hee KIM
1
;
Jong Won KIM
;
Suiyon PARK
;
Eun Hae CHO
;
Eun Ji KIM
;
Sung Sup PARK
;
Jae Seok KIM
;
You Kyung LEE
;
Chang Seok KI
;
Seung Jung KEE
;
Sun Young KONG
;
Sunghee HAN
;
Eul Ju SEO
;
Hyoun Chan CHO
Author Information
1. Diagnostic Genetics Subcommittee, The Korea Association of Quality Assurance for Clinical Pathology, Seoul, Korea. sunnyhk@smc.samsung.co.kr
- Publication Type:Original Article
- Keywords:
External quality assurance;
Diagnostic genetics;
Cytogenetics;
Molecular genetics
- MeSH:
Apolipoproteins E;
Chromosome Aberrations;
Cytogenetics;
Education;
Genetics*;
Huntington Disease;
Karyotype;
Korea*;
Molecular Biology;
Muscular Dystrophy, Duchenne;
Quality Control;
Quality Improvement;
Tuberculosis
- From:Journal of Laboratory Medicine and Quality Assurance
2005;27(1):141-165
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The importance of quality control for dramatically growing genetic tests continues to be emphasized with increasing clinical demands. Diagnostic genetics subcommitee of KSQACP performed two trials for cytogenetic study in 2004. Cytogenetic surveys were performed by 36 laboratories and answered correctly in most laboratories except some problems in karyotype nomenclature, interpretation of FISH test results and the detection of complex cytogenetic abnormalities in hematologic neoplasias. The molecular genetic test surveys included may kinds of tests like M. tuberculosis, HBV, HCV, HPV, leukemias/lymphomas, ApoE genotyping, MTHFR genotyping, BRCA1 & BRCA2, Duchenne muscular dystrophy, and Huntington disease. Each molecular test for HCV, MTHFR genotyping, BRCA1 & BRCA2 analysis and Huntington disease was the first challenge in 2004. Molecular genetic surveys showed excellent results in most of participants. External quality assessment program for genetic analysis in 2004 was proved to be helpful in continuous education and evaluation of quality improvement.
