ЭЛЭГНИЙ АНХДАГЧ ӨМӨНГИЙН ЭРСДЭЛТ ХҮЧИН ЗҮЙЛС БА ДАРХАН ГИСТОХИМИЙН СУДАЛГАА
- Author:
Sarandelger O
1
;
Bayarmaa E
2
;
Erdenetsogt D
2
Author Information
1. Эмгэг судлалын үндэсний төв
2. School of Bio-Medicine of MNUMS
- Publication Type:Journal Article
- Keywords:
Элэгний В, С вирус, архи, элэгний анхдагч өмөн, Beta-catenin
- From:Innovation
2017;11(2):90-92
- CountryMongolia
- Language:Mongolian
-
Abstract:
BACKGROUND. As of 2015 39,1% of all new cancer cases in Mongolia were HCC having
the highest prevalence and it has increased by 4% to the previous year. (Health indicator
– 2015, CHD). Although there are quite a lot researches have been done on general
cause and impacting factors of HCC, the relevance between the mechanism leading
to eventual cancer and the risk factors is still unknown yet. PURPOSE: To define the relevance
of the beta-catenin and P53 expression in HCC with the risk factors of HCC in
Mongolia. RESULT: 1. 50% of HCV infection in men is related with alcohol consumption
and 40% alcohol combined with tobacco consumption. HBV infection has relevance of
46% with tobacco and 52,8% with alcohol consumption. 2. In the first phase of research
in 21 HCC cases beta-catenin was identified in cell nucleus and cytoplasm after immunohistochemistry.
CONCLUSION: 1. It was to observe that HCV infection is commonly
combined with alcohol consumption in HCC cases. 2. Although beta-catenin expression
was high in HCV, HBV infection and alcohol high risk group, the P53 expression was
high among alcohol high risk group. Р < 0.05
