НАТРИ ХӨӨГЧ ПЕПТИД БА ЗҮРХНИЙ АРХАГ ДУТАГДЛЫН ЗАРИМ ЭРСДЭЛТ ХҮЧИН ЗҮЙЛСИЙН ХАМААРАЛ
- VernacularTitle:НАТРИ ХӨӨГЧ ПЕПТИД БА ЗҮРХНИЙ АРХАГ ДУТАГДЛЫН ЗАРИМ ЭРСДЭЛТ ХҮЧИН ЗҮЙЛСИЙН ХАМААРАЛ
- Author:
Batdelger T
1
;
Chingerel KH
1
;
Tsolmon U
1
;
Tungalag Sh
2
;
Dulamkhand B
2
Author Information
1. School of Medicine of MNUMS
2. Express laboratory
- Publication Type:Journal Article
- Keywords:
Chronic heart failure, NT-pro BNP testing, Early diagnosis, Asymptomatic left ventricular dysfunction
- From:Innovation
2017;11(2):19-21
- CountryMongolia
- Language:Mongolian
-
Abstract:
BACKGROUND. Heart failure is the leading cause of the death among non-communicable
diseases. Heart failure is a fatal disease that once its clinical symptoms appeared,
five years of survival rate is 50-75%. Chronic heart failures are the main risk factors arterial
hypertension, diabetes, obesity and dyslipidemia Thus, early diagnosis before its symptoms
are presented and treatment with close monitoring is the most rational and effective
approach for decreasing heart failure diseases and deaths caused by it.
OBJECTIVE. To determine the level of NT-pro BNP in people with high risk of chronic
heart failure and assess its results. METHODS. We conducted hospital-based descriptive
study at State Second Central Hospital and Bayanzurkh District Medical Center. Total of
100 participants aged from 35 to 64 who had no symptom of chronic heart failure however
with high risk were recruited in this study. Based on the document entitled “Heart
failure prevention 2008” of the American Heart Association, old age, arterial hypertension,
diabetes mellitus, heart attack and obesity were considered as higher risks of heart
failure. Risk factors of heart failure were estimated by questionnaire and physical examination.
The level of NT-pro BNP in plasma was determined using FIA8000 analyzer.
According to the guideline produced by the European Society of Cardiology in 2016,
result of the testing is considered “positive” when NT-pro BNP is higher than 125 pg/ml.
Risk factors of chronic heart failure were studied in comparison with two groups which
were NT-pro BNP positive and negative results and their statistically significant difference
were determined. RESULTS. Of 87 participants, 51 (51%) were female and 49(49%) were
male. Half of the participants (51%) were aged between 55-64. Arterial hypertension
was determined in 88% of the participant, 38% were overdose drink of alcohol, therefore
55% were 1,2,3 levels obesity and 36% were diabetic. When determining the NT-pro BNP
level, in 34 cases (34%) were positive. Hence, 31% of the people with arterial hypertension,
9% of the people overdose drink with alcohol, 20% of the people with obesity, 12%
of the people with diabetes showed positive results of NT-pro BNP. When studying the
risk factors of chronic heart failure of the compared two groups of NT-pro BNP positive
and negative results, statistically significant difference (p<0.05) was increased of the
with arterial hypertension and obesity. CONCLUSION. NT-pro BNP is the arterial hypertension
and obesity which is increasing for people compared to the other risking factors
