EFFECT OF CIGARETTE SMOKING ON METABOLISM OF EXPERIMENTAL ANIMAL
- Author:
Dagvasuren Ts
1
;
Darambazar G
1
Author Information
1. Mongolian National University of Medical Sciences, Department of General Sciences
- Publication Type:Journal Article
- Keywords:
nicotine, body weight, glucose, anxiety test
- From:Innovation
2017;11(2):10-11
- CountryMongolia
- Language:Mongolian
-
Abstract:
BACKGROUND
Cigarette smoking is known to reduce appetite and body weight. Even though number of studies explored
different levels of effects of smoking, there are few studies which address short-term effect of
smoking on metabolism.
METHODS
Inbred strain, Balb/cmice (n=20) were used. Mice were divided into two groups control (n=7) and
treatment (n=9) group. Smoking treatment conducted in 5 days consequently in treatment group,
three times a day with cigarette smoke. During experiment both control and treatment groups were
monitored for food intake, water intake, body weight.
RESULTS
In the end of the experiment blood glucose and anxiety levels were measured. In addition, liver, white
adipose tissue and brown adipose issue were sampled comparison. Short-term (5 days) treatment of
smoking of treatment group result in significant difference in food and water intake (p<0.05) as well
as tendency to lowering blood glucose and reduction of mesenterial, perirenal, epidydimal, white
adipose tissues and brown adipose revealed tendency to reduction of mesenterial white adipose with
control group. (Mes. White adipose tissue weights 0.44g in control group, 0.23g in treatment group).
CONCLUSION
There was not significant difference in blood glucose test and anxiety test evaluated by time spent on
alleys and transition between alleys in two groups.
