The prevention and control measures of oropharyngeal flora distribution disorder in patients with chronic obstructive pulmonary disease
10.3969/j.issn.1673-4130.2016.02.015
- VernacularTitle:慢性阻塞性肺疾病患者口咽部菌群分析与菌群分布紊乱的防治措施
- Author:
Fuxin LIU
;
Rongsheng YANG
;
- Publication Type:Journal Article
- Keywords:
pulmonary disease,chronic obstructive;
oropharynx;
bacterial flora distribution;
prevention and control meas-ures
- From:
International Journal of Laboratory Medicine
2016;(2):178-179,182
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the mild chronic obstructive pulmonary disease (COPD) patients′oropharyngeal flora distri‐bution state ,discuss the illness development and prevention measure of COPD patients with oropharyngeal flora disorder .Methods 124 cases of mild COPD patients from the medical center were enrolled in the study to do bacterial culture of swabs ,and 100 cases of healthy subjects were recruited at the same time to do bacterial culture of swabs as control group .The oropharyngeal bacteria distribution state was observed .Results The number of species and detection rates of main pathogenic bacteria and conditional pathogenic bacteria in COPD patients was higher than healthy subjects .In mild COPD patients ,the patients with abnormal oropha‐ryngeal bacteria isolates≥3 ,accounted for 29 .0% (36/124) which was significantly higher than that in control group(8 .0% ,8/100) and the difference was statistically significant(P< 0 .05) .Conclusion Because of immune factors and bad living habits such as smoking ,which could lead to the disorder of body′s normal flora ,infection and make the illness developed .Monitoring of oropharyn‐geal flora distribution state ,and taking active measures to prevent and control it had clinical significance in the prevention of infec‐tion and the development of mild COPD .
