Research Review on TCM Preventing and Treating Parkinson's Disease by Repairing Brain
10.3969/j.issn.1005-5304.2015.02.039
- VernacularTitle:中药修复脑线粒体防治帕金森病研究述评
- Author:
Zhi-ming YANG
;
Mitochondria
;
Xu-zhao LI
;
Fang LU
;
Shu-min LIU
;
- Publication Type:Journal Article
- Keywords:
Chinese herbal medicine;
brain mitochondria;
Parkinson’s disease;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(2):123-125,126
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson’s disease (PD) is a common degenerative disease of central nervous system. Brain mitochondrial dysfunction and structural damage are the important pathogeny of PD. At present, many of Chinese herbal compounds, herbal medicines, and TCM active ingredients are used to prevent and treat PD. The main mechanisms of these medicines are involved in the protection of mitochondrial structure, anti-oxidative stress, anti-calcium dysregulation, mitigation of excitotoxicity, and anti-apoptosis, etc., which also play a comprehensive role through multi-link, multi-level, and multi-target. Through looking up the recent representative literature, the experimental results of Chinese herbal compounds and TCM active ingredients preventing and treating PD through repairing brain mitochondrial structure and function were analyzed and inducted. Many of Chinese herbal compounds and TCM active ingredients were proved to have good effects on PD.